STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXU15147.1Thioredoxin. (105 aa)    
Predicted Functional Partners:
msrB_1
Peptide methionine sulfoxide reductase MsrA / Peptide methionine sulfoxide reductase MsrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.999
msrB_2
Peptide methionine sulfoxide reductase MsrA / Peptide methionine sulfoxide reductase MsrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.999
lpdA
Dihydrolipoamide dehydrogenase of acetoin dehydrogenase.
  
 0.908
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.905
KXU14720.1
Putative Dihydrolipoamide dehydrogenase / Mercuric ion reductase / PF00070 family, FAD-dependent NAD(P)-disulfide oxidoreductase.
   
 0.863
gor
Glutathione reductase.
   
 0.863
KXU15146.1
Hypothetical protein.
       0.800
trxB
Thioredoxin reductase.
  
 0.786
KXU12822.1
Thioredoxin reductase; Overlaps another CDS with the same product name.
  
 0.780
KXU12823.1
Thioredoxin reductase; Overlaps another CDS with the same product name.
  
 0.780
Your Current Organism:
Streptococcus infantis
NCBI taxonomy Id: 68892
Other names: ATCC 700779, CCUG 39817, CIP 105949, DSM 12492, GTC 849, JCM 10157, LMG 18720, LMG:18720, S. infantis, strain O-122
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