node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXU12574.1 | guaB | SINDD18_01512 | SINDD18_01696 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.872 |
KXU12574.1 | murD | SINDD18_01512 | SINDD18_00251 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.813 |
KXU12574.1 | murI | SINDD18_01512 | SINDD18_01062 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.830 |
KXU12574.1 | rdgB | SINDD18_01512 | SINDD18_01061 | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.543 |
KXU13125.1 | KXU13126.1 | SINDD18_01059 | SINDD18_01060 | CBS domain containing protein. | Phosphoesterase. | 0.852 |
KXU13125.1 | guaB | SINDD18_01059 | SINDD18_01696 | CBS domain containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.822 |
KXU13125.1 | murI | SINDD18_01059 | SINDD18_01062 | CBS domain containing protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
KXU13125.1 | rdgB | SINDD18_01059 | SINDD18_01061 | CBS domain containing protein. | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.879 |
KXU13125.1 | rluB | SINDD18_01059 | SINDD18_01055 | CBS domain containing protein. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.785 |
KXU13125.1 | scpA | SINDD18_01059 | SINDD18_01057 | CBS domain containing protein. | Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.800 |
KXU13125.1 | scpB | SINDD18_01059 | SINDD18_01056 | CBS domain containing protein. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.785 |
KXU13125.1 | xerD | SINDD18_01059 | SINDD18_01058 | CBS domain containing protein. | Tyrosine recombinase XerD; Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site. Belongs to the 'phage' integrase family. XerD-like subfamily. | 0.800 |
KXU13126.1 | KXU13125.1 | SINDD18_01060 | SINDD18_01059 | Phosphoesterase. | CBS domain containing protein. | 0.852 |
KXU13126.1 | murI | SINDD18_01060 | SINDD18_01062 | Phosphoesterase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
KXU13126.1 | rdgB | SINDD18_01060 | SINDD18_01061 | Phosphoesterase. | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.946 |
KXU13126.1 | rluB | SINDD18_01060 | SINDD18_01055 | Phosphoesterase. | Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. | 0.785 |
KXU13126.1 | scpA | SINDD18_01060 | SINDD18_01057 | Phosphoesterase. | Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.800 |
KXU13126.1 | scpB | SINDD18_01060 | SINDD18_01056 | Phosphoesterase. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.790 |
KXU13126.1 | xerD | SINDD18_01060 | SINDD18_01058 | Phosphoesterase. | Tyrosine recombinase XerD; Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site. Belongs to the 'phage' integrase family. XerD-like subfamily. | 0.800 |
guaB | KXU12574.1 | SINDD18_01696 | SINDD18_01512 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylformylglycinamidine synthase, synthetase subunit / glutamine amidotransferase subunit. | 0.872 |