STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yidCInner membrane protein translocase component YidC, OxaA protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. (308 aa)    
Predicted Functional Partners:
secG
Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
 0.932
secY
Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 0.850
KXU11995.1
Preprotein translocase subunit SecE; TC 3.A.5.1.1.
   
 0.835
KXU12972.1
Preprotein translocase SecY2 subunit; TC 3.A.5.1.1.
   
 0.816
rpsE
SSU ribosomal protein S5p (S2e); Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
   0.784
atpE
ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 
 0.779
KXU13210.1
V-type ATP synthase subunit K.
  
 
 0.742
KXU14802.1
Cell division protein FtsQ.
  
 
 
 0.740
rplQ
LSU ribosomal protein L17p.
  
 
 0.725
ffh
Signal recognition particle, subunit Ffh; SRP54-like protein, TC 3.A.5.1.1.
   
 0.709
Your Current Organism:
Streptococcus infantis
NCBI taxonomy Id: 68892
Other names: ATCC 700779, CCUG 39817, CIP 105949, DSM 12492, GTC 849, JCM 10157, LMG 18720, LMG:18720, S. infantis, strain O-122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.