STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysKCysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase.
 
 0.991
cysS
Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.962
KXU14729.1
Cystathionine gamma-synthase.
  
 0.943
KXU12044.1
Maltose O-acetyltransferase.
   
 0.932
KXU12079.1
CoA-disulfide reductase; Overlaps another CDS with the same product name.
    
 0.874
KXU12080.1
CoA-disulfide reductase; Overlaps another CDS with the same product name.
    
 0.874
KXU12991.1
Glutamate synthase (NADPH) small chain.
    
 0.731
luxS
S-ribosylhomocysteine lyase / Autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.729
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.726
KXU14855.1
Homoserine dehydrogenase.
 
 
 0.689
Your Current Organism:
Streptococcus infantis
NCBI taxonomy Id: 68892
Other names: ATCC 700779, CCUG 39817, CIP 105949, DSM 12492, GTC 849, JCM 10157, LMG 18720, LMG:18720, S. infantis, strain O-122
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