STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJG19611.1Macro domain, possibly ADP-ribose binding module; COG2110. (158 aa)    
Predicted Functional Partners:
AJG18313.1
Holliday junction DNA helicase; FIG065221.
      0.702
cmk
Cytidylate kinase.
      0.586
cobB-2
NAD-dependent protein deacetylase of SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
 
 0.542
AJG17454.1
NrtR-regulated ADP-ribosyl-glycohydrolase DraG.
    
 0.534
cobB
NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily.
 
 0.533
AJG19610.1
Alcohol dehydrogenase.
  
    0.520
nnrE
NAD(P)HX epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epime [...]
 
 
   0.476
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
  0.415
AJG24245.1
Ankyrin.
 
 
 0.400
Your Current Organism:
Cupriavidus basilensis
NCBI taxonomy Id: 68895
Other names: C. basilensis, CCUG 49340, DSM 11853, LMG 18990, LMG 19474, LMG:18990, LMG:19474, Ralstonia basilensis, Wautersia basilensis, strain RK1
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