STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBNAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily. (252 aa)    
Predicted Functional Partners:
AJG17720.1
Nicotinamide-nucleotide adenylyltransferase, NadM family.
  
 
 0.960
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 0.956
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.928
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.921
AJG19627.1
Nicotinamidase.
  
 0.921
AJG20444.1
Nudix hydrolase family protein.
    
 0.915
AJG20926.1
NAD(P) transhydrogenase alpha subunit.
    
 0.909
AJG22498.1
NAD(P) transhydrogenase alpha subunit.
    
 0.909
AJG20928.1
NAD(P) transhydrogenase alpha subunit.
    
 0.907
AJG22499.1
NAD(P) transhydrogenase alpha subunit.
    
 0.907
Your Current Organism:
Cupriavidus basilensis
NCBI taxonomy Id: 68895
Other names: C. basilensis, CCUG 49340, DSM 11853, LMG 18990, LMG 19474, LMG:18990, LMG:19474, Ralstonia basilensis, Wautersia basilensis, strain RK1
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