| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SBO12225.1 | betB | VME0621_04372 | VME0621_01022 | Hypothetical protein. | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.636 |
| betA | betB | VME0621_01023 | VME0621_01022 | Oxygen-dependent choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.977 |
| betA | betI_1 | VME0621_01023 | VME0621_01021 | Oxygen-dependent choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.942 |
| betA | gbuC_2 | VME0621_01023 | VME0621_01024 | Oxygen-dependent choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Glycine betaine/carnitine transport binding protein GbuC precursor. | 0.830 |
| betA | opuAB | VME0621_01023 | VME0621_01025 | Oxygen-dependent choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Glycine betaine transport system permease protein OpuAB. | 0.687 |
| betA | proV | VME0621_01023 | VME0621_01026 | Oxygen-dependent choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Glycine betaine/L-proline transport ATP-binding protein ProV. | 0.681 |
| betB | SBO12225.1 | VME0621_01022 | VME0621_04372 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Hypothetical protein. | 0.636 |
| betB | betA | VME0621_01022 | VME0621_01023 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Oxygen-dependent choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.977 |
| betB | betI_1 | VME0621_01022 | VME0621_01021 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.901 |
| betB | dat | VME0621_01022 | VME0621_01480 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Diaminobutyrate--2-oxoglutarate aminotransferase. | 0.464 |
| betB | fmt | VME0621_01022 | VME0621_05232 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.659 |
| betB | gbuC_2 | VME0621_01022 | VME0621_01024 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Glycine betaine/carnitine transport binding protein GbuC precursor. | 0.686 |
| betB | iolD | VME0621_01022 | VME0621_03594 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family. | 0.437 |
| betB | opuAB | VME0621_01022 | VME0621_01025 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Glycine betaine transport system permease protein OpuAB. | 0.583 |
| betB | pleC | VME0621_01022 | VME0621_04646 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Non-motile and phage-resistance protein. | 0.445 |
| betB | proV | VME0621_01022 | VME0621_01026 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Glycine betaine/L-proline transport ATP-binding protein ProV. | 0.549 |
| betI_1 | betA | VME0621_01021 | VME0621_01023 | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | Oxygen-dependent choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.942 |
| betI_1 | betB | VME0621_01021 | VME0621_01022 | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | NAD/NADP-dependent betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.901 |
| betI_1 | gbuC_2 | VME0621_01021 | VME0621_01024 | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | Glycine betaine/carnitine transport binding protein GbuC precursor. | 0.856 |
| betI_1 | opuAB | VME0621_01021 | VME0621_01025 | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | Glycine betaine transport system permease protein OpuAB. | 0.656 |