STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpdB4-hydroxyphenylacetate decarboxylase large subunit. (766 aa)    
Predicted Functional Partners:
bssD_2
Benzylsuccinate synthase activating enzyme.
 
  
 0.980
adhE_2
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.951
pdhB
Pyruvate dehydrogenase E1 component subunit beta.
   
 
 0.934
csdA_1
4-hydroxyphenylacetate decarboxylase activating enzyme.
 
  
 0.932
adhE_1
Aldehyde-alcohol dehydrogenase.
 
 
 0.930
pta_2
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.930
adhE_3
Aldehyde-alcohol dehydrogenase.
 
 
 0.929
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.926
pykF
Pyruvate kinase I; Belongs to the pyruvate kinase family.
   
 
 0.918
SBO09989.1
Methylmalonyl-CoA carboxyltransferase 5S subunit.
     
 0.916
Your Current Organism:
Vibrio mediterranei
NCBI taxonomy Id: 689
Other names: ATCC 43341, ATCC BAA-91 [[Vibrio shilonii]], ATCC:BAA:91 [[Vibrio shilonii]], CAIM 316, CCUG 19040, CECT 621, CIP 103203, CIP 107136 [[Vibrio shilonii]], DSM 13774 [[Vibrio shilonii]], DSM 19502, IFO 15635, LMG 11258, LMG 19703 [[Vibrio shilonii]], LMG:11258, LMG:19703 [[Vibrio shilonii]], NBRC 15635, NCTC 11946, V. mediterranei, Vibrio mediterraneus, Vibrio shiloi, Vibrio shiloi (sic) Kushmaro et al. 2001, Vibrio shilonii, Vibrio shilonii corrig. Kushmaro et al. 2001, strain 50, strain AK1 [[Vibrio shilonii]]
Server load: medium (80%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.