STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygfZtRNA-modifying protein YgfZ; Belongs to the GcvT family. (323 aa)    
Predicted Functional Partners:
ybaK_1
Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK.
       0.799
erpA
Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 
 0.680
iscA
Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.
 
 
 0.618
smrA_1
Putative DNA endonuclease SmrA; Belongs to the UPF0115 family.
  
     0.602
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.595
cptB
Antitoxin CptB.
       0.572
SBO12118.1
Putative Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
  
   
 0.498
cvpA
Colicin V production protein.
  
     0.474
grxD
Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily.
  
   
 0.468
bamD
Outer membrane protein assembly factor BamD precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.449
Your Current Organism:
Vibrio mediterranei
NCBI taxonomy Id: 689
Other names: ATCC 43341, ATCC BAA-91 [[Vibrio shilonii]], ATCC:BAA:91 [[Vibrio shilonii]], CAIM 316, CCUG 19040, CECT 621, CIP 103203, CIP 107136 [[Vibrio shilonii]], DSM 13774 [[Vibrio shilonii]], DSM 19502, IFO 15635, LMG 11258, LMG 19703 [[Vibrio shilonii]], LMG:11258, LMG:19703 [[Vibrio shilonii]], NBRC 15635, NCTC 11946, V. mediterranei, Vibrio mediterraneus, Vibrio shiloi, Vibrio shiloi (sic) Kushmaro et al. 2001, Vibrio shilonii, Vibrio shilonii corrig. Kushmaro et al. 2001, strain 50, strain AK1 [[Vibrio shilonii]]
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