Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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dacAD-alanyl-D-alanine carboxypeptidase DacA precursor; Belongs to the peptidase S11 family. (392 aa)    
Predicted Functional Partners:
spoVD
Stage V sporulation protein D; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 
 0.982
ftsI
Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
 
 0.947
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
 
 0.928
dacB
D-alanyl-D-alanine carboxypeptidase DacB precursor.
     
 0.926
mrcA
Penicillin-binding protein 1A.
     
 0.925
pbpG
Penicillin-binding protein 2D; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
 
 0.923
dacC
D-alanyl-D-alanine carboxypeptidase DacC precursor; Belongs to the peptidase S11 family.
  
  
 
0.904
rlmH
Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
 
  
 0.849
mrdB_2
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
   
 0.838
rlpA
Rare lipoprotein A precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
  
 0.781
Your Current Organism:
Vibrio mediterranei
NCBI taxonomy Id: 689
Other names: ATCC 43341, ATCC BAA-91 [[Vibrio shilonii]], ATCC:BAA:91 [[Vibrio shilonii]], CAIM 316, CCUG 19040, CECT 621, CIP 103203, CIP 107136 [[Vibrio shilonii]], DSM 13774 [[Vibrio shilonii]], DSM 19502, IFO 15635, LMG 11258, LMG 19703 [[Vibrio shilonii]], LMG:11258, LMG:19703 [[Vibrio shilonii]], NBRC 15635, NCTC 11946, V. mediterranei, Vibrio mediterraneus, Vibrio shiloi, Vibrio shiloi (sic) Kushmaro et al. 2001, Vibrio shilonii, Vibrio shilonii corrig. Kushmaro et al. 2001, strain 50, strain AK1 [[Vibrio shilonii]]
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