Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rndRibonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (372 aa)    
Predicted Functional Partners:
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
   
 0.966
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 0.957
rpsA
30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
 0.950
SBO10680.1
Ski2-like helicase.
   
 0.944
tmcA
tRNA(Met) cytidine acetyltransferase TmcA; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
   
   0.894
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
 
 0.893
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.875
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
  0.864
hrpB_3
ATP-dependent RNA helicase HrpB.
  
  0.830
hrpB_1
ATP-dependent RNA helicase HrpB.
  
  0.817
Your Current Organism:
Vibrio mediterranei
NCBI taxonomy Id: 689
Other names: ATCC 43341, ATCC BAA-91 [[Vibrio shilonii]], ATCC:BAA:91 [[Vibrio shilonii]], CAIM 316, CCUG 19040, CECT 621, CIP 103203, CIP 107136 [[Vibrio shilonii]], DSM 13774 [[Vibrio shilonii]], DSM 19502, IFO 15635, LMG 11258, LMG 19703 [[Vibrio shilonii]], LMG:11258, LMG:19703 [[Vibrio shilonii]], NBRC 15635, NCTC 11946, V. mediterranei, Vibrio mediterraneus, Vibrio shiloi, Vibrio shiloi (sic) Kushmaro et al. 2001, Vibrio shilonii, Vibrio shilonii corrig. Kushmaro et al. 2001, strain 50, strain AK1 [[Vibrio shilonii]]
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