| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdsA | der | VME0621_04557 | VME0621_04500 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.722 |
| cdsA | dgkA | VME0621_04557 | VME0621_02877 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | 0.925 |
| cdsA | dxr | VME0621_04557 | VME0621_04558 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.944 |
| cdsA | frr | VME0621_04557 | VME0621_04555 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.761 |
| cdsA | ispU | VME0621_04557 | VME0621_04556 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.979 |
| cdsA | pgsA | VME0621_04557 | VME0621_01486 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.953 |
| cdsA | plsC | VME0621_04557 | VME0621_02075 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.925 |
| cdsA | pssA | VME0621_04557 | VME0621_05026 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.918 |
| cdsA | pyrH | VME0621_04557 | VME0621_04554 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.856 |
| cdsA | rseP | VME0621_04557 | VME0621_04559 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Regulator of sigma-E protease RseP. | 0.916 |
| der | cdsA | VME0621_04500 | VME0621_04557 | GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.722 |
| der | frr | VME0621_04500 | VME0621_04555 | GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.499 |
| der | pyrH | VME0621_04500 | VME0621_04554 | GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.706 |
| dgkA | cdsA | VME0621_02877 | VME0621_04557 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.925 |
| dgkA | plsC | VME0621_02877 | VME0621_02075 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.904 |
| dxr | cdsA | VME0621_04558 | VME0621_04557 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.944 |
| dxr | frr | VME0621_04558 | VME0621_04555 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.715 |
| dxr | ispU | VME0621_04558 | VME0621_04556 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.962 |
| dxr | pyrH | VME0621_04558 | VME0621_04554 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.605 |
| dxr | rseP | VME0621_04558 | VME0621_04559 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Regulator of sigma-E protease RseP. | 0.925 |