Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ubiA4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (303 aa)    
Predicted Functional Partners:
GLE_3728
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.921
ubiF
2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1, 4-benzoquinol.
  
  
 0.893
GLE_4979
Pteridine-dependent deoxygenase like protein.
    
  0.872
ubiG
3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 0.849
grxD
Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily.
 
     0.802
ubiH
2-polyprenyl-6-methoxyphenol 4-hydroxylase.
  
  
 0.788
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
 
  
 0.719
GLE_2795
FAD dependent oxidoreductase.
  
 
 0.704
GLE_4223
Flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
 
 
 0.674
GLE_3397
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.644
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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