Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GLE_0144Fatty acid desaturase. (398 aa)    
Predicted Functional Partners:
GLE_4391
Fatty acid desaturase.
    
 0.905
GLE_4392
Oxidoreductase.
     
 0.882
GLE_3067
Oxidoreductase.
     
 0.622
coq7
Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
  
 
   0.611
GLE_0798
Hypothetical protein.
  
     0.598
GLE_1504
Hypothetical protein.
  
     0.499
GLE_2797
Cytochrome P450 family protein.
    
 0.497
GLE_2241
Regulatory protein.
  
     0.490
GLE_0147
Hypothetical protein.
   
   0.465
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.460
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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