Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GLE_0171Lipid A Biosynthesis N-terminal domain. (111 aa)    
Predicted Functional Partners:
GLE_0172
Glycosyl transferase, group 2 family protein.
 
     0.942
GLE_0359
Dolichyl-phosphate-mannose-protein mannosyltransferase.
 
     0.785
GLE_0362
CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase.
  
     0.721
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
  
  
  0.498
GLE_0173
NAD-dependent epimerase/dehydratase family protein.
       0.462
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
     
 0.438
cysG
Putative uroporphyrin-III C-methyltransferase.
  
     0.438
GLE_4558
Outer membrane efflux protein.
  
     0.414
GLE_0361
Lipopolysaccharide core biosynthesis glycosyl transferase.
 
     0.405
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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