node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GLE_0193 | guaA | GLE_0193 | GLE_2893 | Beta-lactamase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.407 |
GLE_0193 | rbsK | GLE_0193 | GLE_0192 | Beta-lactamase. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.723 |
GLE_0254 | GLE_2248 | GLE_0254 | GLE_2248 | Phosphomannomutase. | Oxidoreductase, zinc-binding dehydrogenase family/NAD-binding Rossmann fold. | 0.428 |
GLE_0254 | manA | GLE_0254 | GLE_4230 | Phosphomannomutase. | Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.987 |
GLE_0254 | prs | GLE_0254 | GLE_3809 | Phosphomannomutase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.937 |
GLE_0254 | rbsK | GLE_0254 | GLE_0192 | Phosphomannomutase. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.905 |
GLE_0254 | rbsK-2 | GLE_0254 | GLE_1054 | Phosphomannomutase. | Kinase, pfkB family protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.905 |
GLE_0254 | rpiA | GLE_0254 | GLE_0882 | Phosphomannomutase. | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.917 |
GLE_0254 | tktA | GLE_0254 | GLE_0948 | Phosphomannomutase. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.923 |
GLE_0924 | rbsK | GLE_0924 | GLE_0192 | Inosine-uridine preferring nucleoside hydrolase. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.951 |
GLE_0924 | rbsK-2 | GLE_0924 | GLE_1054 | Inosine-uridine preferring nucleoside hydrolase. | Kinase, pfkB family protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.923 |
GLE_2248 | GLE_0254 | GLE_2248 | GLE_0254 | Oxidoreductase, zinc-binding dehydrogenase family/NAD-binding Rossmann fold. | Phosphomannomutase. | 0.428 |
GLE_2248 | manA | GLE_2248 | GLE_4230 | Oxidoreductase, zinc-binding dehydrogenase family/NAD-binding Rossmann fold. | Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.478 |
GLE_2248 | rbsK | GLE_2248 | GLE_0192 | Oxidoreductase, zinc-binding dehydrogenase family/NAD-binding Rossmann fold. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.659 |
GLE_2248 | rbsK-2 | GLE_2248 | GLE_1054 | Oxidoreductase, zinc-binding dehydrogenase family/NAD-binding Rossmann fold. | Kinase, pfkB family protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.659 |
GLE_2248 | rpiA | GLE_2248 | GLE_0882 | Oxidoreductase, zinc-binding dehydrogenase family/NAD-binding Rossmann fold. | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.444 |
GLE_2248 | tktA | GLE_2248 | GLE_0948 | Oxidoreductase, zinc-binding dehydrogenase family/NAD-binding Rossmann fold. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.487 |
guaA | GLE_0193 | GLE_2893 | GLE_0193 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Beta-lactamase. | 0.407 |
guaA | prs | GLE_2893 | GLE_3809 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.786 |
guaA | rbsK | GLE_2893 | GLE_0192 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.639 |