STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLE_0246Oxidoreductase. (288 aa)    
Predicted Functional Partners:
mmsA
Methylmalonate-semialdehyde dehydrogenase (acylating).
 
 
 0.875
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.793
prpE
propionate--CoA ligase.
    
  0.793
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
    
 0.787
GLE_4319
Branched-chain alpha-keto acid dehydrogenase subunit E2.
     
 0.780
GLE_2729
Quinone oxidoreductase, YhdH/YhfP family.
     
  0.778
GLE_2603
Xylose isomerase; Belongs to the hyi family.
  
 
 0.775
paaG
enoyl-CoA hydratase.
 
 0.733
GLE_2141
D-isomer specific 2-hydroxyacid dehydrogenase.
 
  
 0.701
mmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.692
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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