GLE_0610 protein (Lysobacter enzymogenes) - STRING interaction network

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[Homology]

Score

GLE_0610

GTP-binding protein. (182 aa)

Predicted Functional Partners:

GLE_0607

0.984

ftsY

0.894

GLE_0608

0.830

ffh

0.779

GLE_0609

0.773

secY

0.497

rplE

0.484

rplN

0.484

rpmC

0.484

Your Current Organism:

Lysobacter enzymogenes

NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLE_0607	GLE_0608	GLE_0607	GLE_0608	roadblock/LC7 domain family.	Hypothetical protein.	0.514
GLE_0607	GLE_0610	GLE_0607	GLE_0610	roadblock/LC7 domain family.	GTP-binding protein.	0.984
GLE_0608	GLE_0607	GLE_0608	GLE_0607	Hypothetical protein.	roadblock/LC7 domain family.	0.514
GLE_0608	GLE_0609	GLE_0608	GLE_0609	Hypothetical protein.	Hypothetical protein.	0.465
GLE_0608	GLE_0610	GLE_0608	GLE_0610	Hypothetical protein.	GTP-binding protein.	0.830
GLE_0609	GLE_0608	GLE_0609	GLE_0608	Hypothetical protein.	Hypothetical protein.	0.465
GLE_0609	GLE_0610	GLE_0609	GLE_0610	Hypothetical protein.	GTP-binding protein.	0.773
GLE_0610	GLE_0607	GLE_0610	GLE_0607	GTP-binding protein.	roadblock/LC7 domain family.	0.984
GLE_0610	GLE_0608	GLE_0610	GLE_0608	GTP-binding protein.	Hypothetical protein.	0.830
GLE_0610	GLE_0609	GLE_0610	GLE_0609	GTP-binding protein.	Hypothetical protein.	0.773
GLE_0610	ffh	GLE_0610	GLE_3257	GTP-binding protein.	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]	0.779
GLE_0610	ftsY	GLE_0610	GLE_3534	GTP-binding protein.	Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	0.894
GLE_0610	rplE	GLE_0610	GLE_3778	GTP-binding protein.	Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.484
GLE_0610	rplN	GLE_0610	GLE_3780	GTP-binding protein.	Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.484
GLE_0610	rpmC	GLE_0610	GLE_3782	GTP-binding protein.	Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	0.484
GLE_0610	secY	GLE_0610	GLE_3770	GTP-binding protein.	Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.497
ffh	GLE_0610	GLE_3257	GLE_0610	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]	GTP-binding protein.	0.779
ffh	ftsY	GLE_3257	GLE_3534	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]	Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.	0.997
ffh	rplE	GLE_3257	GLE_3778	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]	Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.891
ffh	rplN	GLE_3257	GLE_3780	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]	Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.865