| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GLE_0659 | GLE_0662 | GLE_0659 | GLE_0662 | Membrane protein. | Haloacid dehalogenase-like hydrolase. | 0.508 |
| GLE_0659 | rsmC | GLE_0659 | GLE_0660 | Membrane protein. | Ribosomal RNA small subunit methyltransferase C; Belongs to the methyltransferase superfamily. | 0.555 |
| GLE_0659 | rsuA | GLE_0659 | GLE_0661 | Membrane protein. | Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family. | 0.549 |
| GLE_0662 | GLE_0659 | GLE_0662 | GLE_0659 | Haloacid dehalogenase-like hydrolase. | Membrane protein. | 0.508 |
| GLE_0662 | rsmC | GLE_0662 | GLE_0660 | Haloacid dehalogenase-like hydrolase. | Ribosomal RNA small subunit methyltransferase C; Belongs to the methyltransferase superfamily. | 0.744 |
| GLE_0662 | rsuA | GLE_0662 | GLE_0661 | Haloacid dehalogenase-like hydrolase. | Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family. | 0.746 |
| hfq | mraW | GLE_1510 | GLE_4138 | RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.587 |
| hfq | rsmC | GLE_1510 | GLE_0660 | RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribosomal RNA small subunit methyltransferase C; Belongs to the methyltransferase superfamily. | 0.514 |
| hfq | rsmI | GLE_1510 | GLE_4142 | RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.640 |
| mraW | hfq | GLE_4138 | GLE_1510 | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.587 |
| mraW | obgE | GLE_4138 | GLE_3291 | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.548 |
| mraW | rsmC | GLE_4138 | GLE_0660 | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Ribosomal RNA small subunit methyltransferase C; Belongs to the methyltransferase superfamily. | 0.759 |
| mraW | rsmI | GLE_4138 | GLE_4142 | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.874 |
| obgE | mraW | GLE_3291 | GLE_4138 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.548 |
| obgE | rplA | GLE_3291 | GLE_3800 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.911 |
| obgE | rsmC | GLE_3291 | GLE_0660 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal RNA small subunit methyltransferase C; Belongs to the methyltransferase superfamily. | 0.771 |
| rplA | obgE | GLE_3800 | GLE_3291 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.911 |
| rplA | rpoB | GLE_3800 | GLE_3797 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.997 |
| rplA | rsmC | GLE_3800 | GLE_0660 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosomal RNA small subunit methyltransferase C; Belongs to the methyltransferase superfamily. | 0.507 |
| rpoB | rplA | GLE_3797 | GLE_3800 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.997 |