STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLE_0737Hydrolase, alpha/beta hydrolase fold family protein. (351 aa)    
Predicted Functional Partners:
GLE_4921
NAD dependent epimerase/dehydratase family.
  
     0.693
GLE_4924
Cupin domain protein.
  
  
  0.664
GLE_2369
Esterase/lipase/thioesterase domain-containing protein.
  
     0.652
GLE_2003
Hydrolase, alpha/beta fold family.
  
     0.600
GLE_4077
Hydrolase, alpha/beta fold family protein.
  
     0.588
GLE_4894
Amino acid adenylation domain protein.
   
 0.567
GLE_2190
Oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
  0.536
mutA
methylmalonyl-CoA mutase, alpha subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
     
 0.471
pheA
Chorismate mutase/prephenate dehydratase/ACT domain.
     
 0.447
apaH
Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
  0.430
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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