Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GLE_0778Extracellular ribonuclease precursor. (604 aa)    
Predicted Functional Partners:
GLE_5425
Nuclease.
  
 0.928
GLE_0777
Hypothetical protein.
       0.727
GLE_1384
mutT/nudix family protein.
 
  
  0.720
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.676
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.645
GLE_4313
Nuclease.
 
  
 0.581
GLE_1466
Hypothetical protein.
  
     0.568
GLE_0196
Large Ala/Gln-rich protein.
  
     0.552
GLE_0362
CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase.
  
     0.546
GLE_5432
Ion channel.
  
     0.543
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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