node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GLE_0360 | GLE_1665 | GLE_0360 | GLE_1665 | O-Antigen polymerase. | Heptosyltransferase. | 0.632 |
GLE_0360 | kdkA | GLE_0360 | GLE_1666 | O-Antigen polymerase. | Lipopolysaccharide kinase (Kdo/WaaP) family; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. | 0.521 |
GLE_0360 | waaA | GLE_0360 | GLE_0803 | O-Antigen polymerase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.915 |
GLE_0366 | GLE_1197 | GLE_0366 | GLE_1197 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | Arabinose 5-phosphate isomerase. | 0.666 |
GLE_0366 | GLE_1665 | GLE_0366 | GLE_1665 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | Heptosyltransferase. | 0.594 |
GLE_0366 | kdsB | GLE_0366 | GLE_3031 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.575 |
GLE_0366 | lpxA | GLE_0366 | GLE_3382 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.702 |
GLE_0366 | lpxB | GLE_0366 | GLE_3384 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.752 |
GLE_0366 | lpxK | GLE_0366 | GLE_3032 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.763 |
GLE_0366 | lpxL | GLE_0366 | GLE_0801 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.913 |
GLE_0366 | waaA | GLE_0366 | GLE_0803 | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.969 |
GLE_1197 | GLE_0366 | GLE_1197 | GLE_0366 | Arabinose 5-phosphate isomerase. | Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase. | 0.666 |
GLE_1197 | GLE_1665 | GLE_1197 | GLE_1665 | Arabinose 5-phosphate isomerase. | Heptosyltransferase. | 0.501 |
GLE_1197 | kdsB | GLE_1197 | GLE_3031 | Arabinose 5-phosphate isomerase. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.910 |
GLE_1197 | lpxA | GLE_1197 | GLE_3382 | Arabinose 5-phosphate isomerase. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.862 |
GLE_1197 | lpxB | GLE_1197 | GLE_3384 | Arabinose 5-phosphate isomerase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.833 |
GLE_1197 | lpxK | GLE_1197 | GLE_3032 | Arabinose 5-phosphate isomerase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.865 |
GLE_1197 | lpxL | GLE_1197 | GLE_0801 | Arabinose 5-phosphate isomerase. | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.742 |
GLE_1197 | waaA | GLE_1197 | GLE_0803 | Arabinose 5-phosphate isomerase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.859 |
GLE_1665 | GLE_0360 | GLE_1665 | GLE_0360 | Heptosyltransferase. | O-Antigen polymerase. | 0.632 |