STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (329 aa)    
Predicted Functional Partners:
thrC
Threonine synthase.
 
 0.999
GLE_0829
Aspartate kinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 0.999
GLE_1124
Homoserine dehydrogenase.
 0.995
metB
O-succinylhomoserine (thiol)-lyase.
    
 0.948
lysA
Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
 0.948
mdeA
Methionine gamma-lyase.
    
 0.948
ilvE
Branched-chain amino acid aminotransferase.
  
 
 0.917
metH
Methionine synthase.
    
 0.908
sdaA
L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.907
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
 0.906
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.