STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gorGlutathione reductase. (457 aa)    
Predicted Functional Partners:
tkB
Transketolase.
 
 0.985
gltB
Glutamine amidotransferases class-II/glutamate synthase.
    
 0.941
sucB
Dihydrolipoyllysine-residue succinyltransferase, E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.927
pdhB
Pyruvate dehydrogenase E1 component, beta subunit.
 
 0.927
aceF
Dihydrolipoyllysine-residue acetyltransferase.
 0.925
gshB
Glutathione synthase; Belongs to the prokaryotic GSH synthase family.
     
 0.916
GLE_4319
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.914
GLE_2732
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
 
  
 0.911
GLE_3053
Glutathione S-transferase; Belongs to the GST superfamily.
  
  
 0.906
btuE
Glutathione peroxidase/vitamin B12 transport periplasmic protein btuE; Belongs to the glutathione peroxidase family.
   
 0.904
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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