| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GLE_0360 | GLE_1665 | GLE_0360 | GLE_1665 | O-Antigen polymerase. | Heptosyltransferase. | 0.752 |
| GLE_0360 | kdkA | GLE_0360 | GLE_1666 | O-Antigen polymerase. | Lipopolysaccharide kinase (Kdo/WaaP) family; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. | 0.494 |
| GLE_0360 | waaA | GLE_0360 | GLE_0803 | O-Antigen polymerase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.892 |
| GLE_1665 | GLE_0360 | GLE_1665 | GLE_0360 | Heptosyltransferase. | O-Antigen polymerase. | 0.752 |
| GLE_1665 | GLE_2171 | GLE_1665 | GLE_2171 | Heptosyltransferase. | Proton-translocating NADH-quinone oxidoreductase, chain M family protein. | 0.739 |
| GLE_1665 | hisB | GLE_1665 | GLE_1900 | Heptosyltransferase. | Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.725 |
| GLE_1665 | kdkA | GLE_1665 | GLE_1666 | Heptosyltransferase. | Lipopolysaccharide kinase (Kdo/WaaP) family; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. | 0.945 |
| GLE_1665 | lpxK | GLE_1665 | GLE_3032 | Heptosyltransferase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.729 |
| GLE_1665 | nuoB | GLE_1665 | GLE_2160 | Heptosyltransferase. | NADH-quinone oxidoreductase, B subunit family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.730 |
| GLE_1665 | nuoC | GLE_1665 | GLE_2161 | Heptosyltransferase. | NADH dehydrogenase, subunit C family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. | 0.726 |
| GLE_1665 | nuoD | GLE_1665 | GLE_2162 | Heptosyltransferase. | NADH dehydrogenase D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. | 0.727 |
| GLE_1665 | nuoN | GLE_1665 | GLE_2172 | Heptosyltransferase. | Proton-translocating NADH-quinone oxidoreductase, chain N family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. | 0.733 |
| GLE_1665 | waaA | GLE_1665 | GLE_0803 | Heptosyltransferase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.960 |
| GLE_2171 | GLE_1665 | GLE_2171 | GLE_1665 | Proton-translocating NADH-quinone oxidoreductase, chain M family protein. | Heptosyltransferase. | 0.739 |
| GLE_2171 | nuoB | GLE_2171 | GLE_2160 | Proton-translocating NADH-quinone oxidoreductase, chain M family protein. | NADH-quinone oxidoreductase, B subunit family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.999 |
| GLE_2171 | nuoC | GLE_2171 | GLE_2161 | Proton-translocating NADH-quinone oxidoreductase, chain M family protein. | NADH dehydrogenase, subunit C family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. | 0.999 |
| GLE_2171 | nuoD | GLE_2171 | GLE_2162 | Proton-translocating NADH-quinone oxidoreductase, chain M family protein. | NADH dehydrogenase D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. | 0.999 |
| GLE_2171 | nuoN | GLE_2171 | GLE_2172 | Proton-translocating NADH-quinone oxidoreductase, chain M family protein. | Proton-translocating NADH-quinone oxidoreductase, chain N family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. | 0.999 |
| hisB | GLE_1665 | GLE_1900 | GLE_1665 | Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Heptosyltransferase. | 0.725 |
| hisB | waaA | GLE_1900 | GLE_0803 | Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.597 |