Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pilZ-2Type IV pilus assembly protein PilZ. (119 aa)    
Predicted Functional Partners:
GLE_1812
Sensory box-containing diguanylate cyclase/cyclic diguanylate phosphodiesterase.
  
 
   0.948
pilB
Type IV pilus assembly protein.
    
 
 0.883
holB
DNA polymerase III subunit delta prime.
 
   
 0.880
pilL
Hpt domain protein; Response regulator receiver domain/histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CheW-like domain.
 
 
 
 0.862
pilM
Type IV pilus assembly protein.
  
   
 0.855
mltG
Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
       0.842
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.842
pilP
Type IV assembly protein.
  
   
 0.827
pilN
Type IV pilus assembly protein.
  
   
 0.825
pilO
Type IV assembly protein.
  
   
 0.817
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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