Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mvaBHydroxymethylglutaryl-CoA lyase. (303 aa)    
Predicted Functional Partners:
GLE_1954
enoyl-CoA hydratase.
 
 0.995
GLE_1950
methylcrotonoyl-CoA carboxylase subunit alpha.
 
 
 0.984
GLE_4228
3-oxoacid CoA-transferase, A subunit family.
  
 
 0.925
GLE_1967
methylcrotonoyl-CoA carboxylase.
 0.924
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.922
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.921
scoB
succinyl-CoA:3-ketoacid-coenzyme A transferase, subunit B.
  
 
 0.919
GLE_1971
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.910
GLE_2914
3-ketoacyl-CoA thiolase A; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.910
GLE_5043
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.910
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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