Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GLE_2003Hydrolase, alpha/beta fold family. (291 aa)    
Predicted Functional Partners:
GLE_2004
Hypothetical protein.
 
     0.787
dmpD
2-hydroxymuconic semialdehyde hydrolase.
  
     0.738
GLE_0737
Hydrolase, alpha/beta hydrolase fold family protein.
  
     0.600
GLE_0232
Hydrolase, alpha/beta hydrolase fold family protein.
  
     0.521
GLE_0202
AMP-binding enzyme.
 
 
 0.493
GLE_4894
Amino acid adenylation domain protein.
   
 0.462
putA
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.457
mutA
methylmalonyl-CoA mutase, alpha subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
     
  0.455
GLE_2508
Hydrolase, alpha/beta fold family.
  
     0.450
GLE_2995
NAD dependent epimerase/dehydratase family.
    
 0.411
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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