node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GLE_2244 | GLE_5196 | GLE_2244 | GLE_5196 | Glucosamine-fructose-6-phosphate aminotransferase. | SIS domain protein. | 0.991 |
GLE_2244 | glmM | GLE_2244 | GLE_2150 | Glucosamine-fructose-6-phosphate aminotransferase. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.819 |
GLE_2244 | glmU | GLE_2244 | GLE_0692 | Glucosamine-fructose-6-phosphate aminotransferase. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.950 |
GLE_2244 | manA | GLE_2244 | GLE_4230 | Glucosamine-fructose-6-phosphate aminotransferase. | Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.664 |
GLE_2244 | nagA-2 | GLE_2244 | GLE_5197 | Glucosamine-fructose-6-phosphate aminotransferase. | N-acetylglucosamine-6-phosphate deacetylase. | 0.652 |
GLE_5196 | GLE_2244 | GLE_5196 | GLE_2244 | SIS domain protein. | Glucosamine-fructose-6-phosphate aminotransferase. | 0.991 |
GLE_5196 | glmM | GLE_5196 | GLE_2150 | SIS domain protein. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.927 |
GLE_5196 | glmS | GLE_5196 | GLE_0702 | SIS domain protein. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.762 |
GLE_5196 | nagA-2 | GLE_5196 | GLE_5197 | SIS domain protein. | N-acetylglucosamine-6-phosphate deacetylase. | 0.997 |
accD | glmM | GLE_2149 | GLE_2150 | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.689 |
folP | glmM | GLE_1508 | GLE_2150 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.757 |
glmM | GLE_2244 | GLE_2150 | GLE_2244 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-fructose-6-phosphate aminotransferase. | 0.819 |
glmM | GLE_5196 | GLE_2150 | GLE_5196 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | SIS domain protein. | 0.927 |
glmM | accD | GLE_2150 | GLE_2149 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.689 |
glmM | folP | GLE_2150 | GLE_1508 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.757 |
glmM | glmS | GLE_2150 | GLE_0702 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.907 |
glmM | glmU | GLE_2150 | GLE_0692 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.996 |
glmM | manA | GLE_2150 | GLE_4230 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.808 |
glmM | murA | GLE_2150 | GLE_1199 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.732 |
glmM | murC | GLE_2150 | GLE_4130 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.700 |