Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
GLE_2234Gram-negative bacterial tonB protein. (157 aa)    
Predicted Functional Partners:
GLE_3343
Lipoprotein.
  
 
   0.701
GLE_4802
AMP nucleosidase.
  
     0.676
GLE_4994
Immunogenic 75 kDa protein PG4.
  
 
   0.643
GLE_3630
Membrane protein.
  
     0.519
GLE_1657
Transglycosylase SLT domain/LysM domain.
  
  
  0.459
GLE_4254
Outer membrane protein.
    
   0.447
GLE_2271
Beta-hexosaminidase.
  
     0.412
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
     0.411
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
       0.410
GLE_3584
Oar protein.
  
   0.410
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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