lig protein (Lysobacter enzymogenes) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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[Homology]

Score

lig

DNA ligase. (532 aa)

Predicted Functional Partners:

ysh1

0.996

dnaN

0.878

polA-2

0.864

ku

0.757

topB

0.700

atpC

0.640

polA

0.624

hisB

0.609

GLE_2473

0.546

holB

0.511

Your Current Organism:

Lysobacter enzymogenes

NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLE_2473	lig	GLE_2473	GLE_2471	Hypothetical protein.	DNA ligase.	0.546
GLE_2473	ysh1	GLE_2473	GLE_2472	Hypothetical protein.	Endoribonuclease YSH1.	0.546
atpC	lig	GLE_0690	GLE_2471	ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.	DNA ligase.	0.640
atpC	ysh1	GLE_0690	GLE_2472	ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Endoribonuclease YSH1.	0.641
dnaN	holB	GLE_5338	GLE_1698	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit delta prime.	0.994
dnaN	lig	GLE_5338	GLE_2471	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA ligase.	0.878
dnaN	polA	GLE_5338	GLE_3872	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I.	0.916
dnaN	polA-2	GLE_5338	GLE_4940	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.987
dnaN	topB	GLE_5338	GLE_2415	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA topoisomerase III.	0.772
hisB	lig	GLE_1900	GLE_2471	Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.	DNA ligase.	0.609
holB	dnaN	GLE_1698	GLE_5338	DNA polymerase III subunit delta prime.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.994
holB	lig	GLE_1698	GLE_2471	DNA polymerase III subunit delta prime.	DNA ligase.	0.511
holB	polA	GLE_1698	GLE_3872	DNA polymerase III subunit delta prime.	DNA polymerase I.	0.756
holB	polA-2	GLE_1698	GLE_4940	DNA polymerase III subunit delta prime.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.834
ku	lig	GLE_3697	GLE_2471	Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	DNA ligase.	0.757
ku	topB	GLE_3697	GLE_2415	Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	DNA topoisomerase III.	0.711
lig	GLE_2473	GLE_2471	GLE_2473	DNA ligase.	Hypothetical protein.	0.546
lig	atpC	GLE_2471	GLE_0690	DNA ligase.	ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.640
lig	dnaN	GLE_2471	GLE_5338	DNA ligase.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.878
lig	hisB	GLE_2471	GLE_1900	DNA ligase.	Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.	0.609