Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
GLE_2565Histidine kinase. (454 aa)    
Predicted Functional Partners:
GLE_2564
Transcriptional regulatory protein, C terminal - DNA-binding response regulator.
 
  0.961
phoP
DNA-binding response regulator.
  
  0.853
GLE_4323
DNA-binding response regulator.
  
  0.845
GLE_4780
Transcriptional regulatory protein, C terminal - DNA-binding response regulator.
  
  0.840
phoB
Phosphate regulon transcriptional regulatory protein PhoB.
  
  0.839
GLE_4889
DNA-binding response regulator.
  
  0.839
GLE_1780
Two component heavy metal response transcriptional regulator.
  
  0.837
GLE_1628
DNA-binding response regulator.
  
  0.836
GLE_0631
DNA-binding response regulator.
  
  0.835
pilH-2
Type IV pilus assembly protein.
  
  0.834
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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