kmo-2 protein (Lysobacter enzymogenes) - STRING interaction network

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kmo-2

Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (457 aa)

Predicted Functional Partners:

kynU

0.995

GLE_2676

0.906

nbaC

0.900

kmo

0.887

sbcB

0.842

GLE_4565

0.759

GLE_2674

0.691

GLE_2681

0.652

GLE_1003

0.618

yagT

0.601

Your Current Organism:

Lysobacter enzymogenes

NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLE_1003	kmo-2	GLE_1003	GLE_2679	Iron-sulfur cluster-binding protein, Rieske family.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.	0.618
GLE_2674	GLE_2676	GLE_2674	GLE_2676	Endoribonuclease L-PSP.	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	0.883
GLE_2674	kmo-2	GLE_2674	GLE_2679	Endoribonuclease L-PSP.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.	0.691
GLE_2674	kynU	GLE_2674	GLE_2678	Endoribonuclease L-PSP.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.	0.651
GLE_2674	nbaC	GLE_2674	GLE_2675	Endoribonuclease L-PSP.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.892
GLE_2674	sbcB	GLE_2674	GLE_2680	Endoribonuclease L-PSP.	Exodeoxyribonuclease I.	0.490
GLE_2676	GLE_2674	GLE_2676	GLE_2674	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	Endoribonuclease L-PSP.	0.883
GLE_2676	GLE_2681	GLE_2676	GLE_2681	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	Hypothetical protein.	0.510
GLE_2676	kmo	GLE_2676	GLE_0549	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	Kynurenine 3-monooxygenase.	0.767
GLE_2676	kmo-2	GLE_2676	GLE_2679	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.	0.906
GLE_2676	kynU	GLE_2676	GLE_2678	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.	0.901
GLE_2676	nbaC	GLE_2676	GLE_2675	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.994
GLE_2676	sbcB	GLE_2676	GLE_2680	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	Exodeoxyribonuclease I.	0.593
GLE_2681	GLE_2676	GLE_2681	GLE_2676	Hypothetical protein.	2-amino-3-carboxymuconate 6-semialdehyde decarboxylase.	0.510
GLE_2681	kmo-2	GLE_2681	GLE_2679	Hypothetical protein.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.	0.652
GLE_2681	kynU	GLE_2681	GLE_2678	Hypothetical protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.	0.590
GLE_2681	nbaC	GLE_2681	GLE_2675	Hypothetical protein.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.412
GLE_2681	sbcB	GLE_2681	GLE_2680	Hypothetical protein.	Exodeoxyribonuclease I.	0.652
GLE_4565	kmo-2	GLE_4565	GLE_2679	2Fe-2S iron-sulfur cluster binding domain.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.	0.759
GLE_4565	yagT	GLE_4565	GLE_1131	2Fe-2S iron-sulfur cluster binding domain.	Xanthine dehydrogenase.	0.669

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