| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GLE_1188 | rne | GLE_1188 | GLE_2949 | glmZ(sRNA)-inactivating NTPase; Displays ATPase and GTPase activities. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.855 |
| GLE_3468 | pnp | GLE_3468 | GLE_2180 | DEAD/DEAH box helicase/helicase conserved C-terminal domain; Belongs to the DEAD box helicase family. | Polyribonucleotide nucleotidyltransferase, RNA binding domain; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.851 |
| GLE_3468 | rne | GLE_3468 | GLE_2949 | DEAD/DEAH box helicase/helicase conserved C-terminal domain; Belongs to the DEAD box helicase family. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.534 |
| GLE_3468 | rpsA | GLE_3468 | GLE_2925 | DEAD/DEAH box helicase/helicase conserved C-terminal domain; Belongs to the DEAD box helicase family. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.763 |
| dapF | lysA | GLE_4534 | GLE_3732 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.978 |
| dapF | rne | GLE_4534 | GLE_2949 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.518 |
| eno | pnp | GLE_1488 | GLE_2180 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Polyribonucleotide nucleotidyltransferase, RNA binding domain; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.826 |
| eno | rne | GLE_1488 | GLE_2949 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.874 |
| eno | rpsA | GLE_1488 | GLE_2925 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.716 |
| hfq | pnp | GLE_1510 | GLE_2180 | RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Polyribonucleotide nucleotidyltransferase, RNA binding domain; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.847 |
| hfq | rho | GLE_1510 | GLE_4918 | RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.524 |
| hfq | rne | GLE_1510 | GLE_2949 | RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.570 |
| hfq | rnr | GLE_1510 | GLE_3338 | RNA-binding protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.576 |
| lysA | dapF | GLE_3732 | GLE_4534 | Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.978 |
| lysA | pnp | GLE_3732 | GLE_2180 | Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Polyribonucleotide nucleotidyltransferase, RNA binding domain; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.473 |
| lysA | rho | GLE_3732 | GLE_4918 | Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.636 |
| lysA | rne | GLE_3732 | GLE_2949 | Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.515 |
| lysA | rpsA | GLE_3732 | GLE_2925 | Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.446 |
| pnp | GLE_3468 | GLE_2180 | GLE_3468 | Polyribonucleotide nucleotidyltransferase, RNA binding domain; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | DEAD/DEAH box helicase/helicase conserved C-terminal domain; Belongs to the DEAD box helicase family. | 0.851 |
| pnp | eno | GLE_2180 | GLE_1488 | Polyribonucleotide nucleotidyltransferase, RNA binding domain; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.826 |