Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GLE_3007Diguanylate cyclase. (355 aa)    
Predicted Functional Partners:
GLE_5164
Response regulator protein.
 
    0.976
GLE_2281
Response regulator.
 
  
 0.969
GLE_1812
Sensory box-containing diguanylate cyclase/cyclic diguanylate phosphodiesterase.
 
 
 0.933
GLE_5222
Diguanylate cyclase.
 
      0.891
GLE_5368
Sensor histidine kinase.
 
    
 0.879
GLE_3006
Hypothetical protein.
       0.801
GLE_3008
Hypothetical protein.
       0.737
GLE_0894
Sensory box protein.
 
0.714
GLE_0632
Sensory box histidine kinase.
 
 0.698
morA
PAS domain protein.
 
0.682
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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