Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GLE_3091Two component transcriptional regulator, winged helix family. (255 aa)    
Predicted Functional Partners:
GLE_0632
Sensory box histidine kinase.
  
 0.891
GLE_0164
Sensory box histidine kinase.
  
 0.655
GLE_1142
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 0.646
GLE_1143
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 0.646
GLE_4341
Sensor histidine kinase.
 
 0.642
pilL
Hpt domain protein; Response regulator receiver domain/histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CheW-like domain.
  
 0.630
GLE_3438
Diguanylate cyclase.
  
 0.559
GLE_2449
Histidine kinase.
  
 0.512
GLE_1781
Putative heavy metal histidine sensor kinase; Member of a two-component regulatory system.
   
  0.511
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.472
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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