node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GLE_0880 | GLE_2206 | GLE_0880 | GLE_2206 | DNA polymerase IV. | Hypothetical protein. | 0.776 |
GLE_0880 | lexA-2 | GLE_0880 | GLE_3205 | DNA polymerase IV. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.669 |
GLE_0880 | recA | GLE_0880 | GLE_3203 | DNA polymerase IV. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.658 |
GLE_2205 | GLE_2206 | GLE_2205 | GLE_2206 | nucleotidyltransferase/DNA polymerase involved in DNA repair. | Hypothetical protein. | 0.998 |
GLE_2205 | lexA-2 | GLE_2205 | GLE_3205 | nucleotidyltransferase/DNA polymerase involved in DNA repair. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.703 |
GLE_2205 | recA | GLE_2205 | GLE_3203 | nucleotidyltransferase/DNA polymerase involved in DNA repair. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.675 |
GLE_2206 | GLE_0880 | GLE_2206 | GLE_0880 | Hypothetical protein. | DNA polymerase IV. | 0.776 |
GLE_2206 | GLE_2205 | GLE_2206 | GLE_2205 | Hypothetical protein. | nucleotidyltransferase/DNA polymerase involved in DNA repair. | 0.998 |
GLE_2206 | dinB | GLE_2206 | GLE_5281 | Hypothetical protein. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.776 |
GLE_2206 | lexA-2 | GLE_2206 | GLE_3205 | Hypothetical protein. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.574 |
GLE_2206 | recA | GLE_2206 | GLE_3203 | Hypothetical protein. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.532 |
GLE_3204 | GLE_3206 | GLE_3204 | GLE_3206 | Hypothetical protein. | MarR family N-acetyltransferase transcriptional regulator. | 0.537 |
GLE_3204 | lexA-2 | GLE_3204 | GLE_3205 | Hypothetical protein. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.800 |
GLE_3204 | recA | GLE_3204 | GLE_3203 | Hypothetical protein. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.658 |
GLE_3204 | recX | GLE_3204 | GLE_3202 | Hypothetical protein. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.574 |
GLE_3206 | GLE_3204 | GLE_3206 | GLE_3204 | MarR family N-acetyltransferase transcriptional regulator. | Hypothetical protein. | 0.537 |
GLE_3206 | lexA-2 | GLE_3206 | GLE_3205 | MarR family N-acetyltransferase transcriptional regulator. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.543 |
GLE_3206 | recA | GLE_3206 | GLE_3203 | MarR family N-acetyltransferase transcriptional regulator. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.539 |
GLE_3206 | recX | GLE_3206 | GLE_3202 | MarR family N-acetyltransferase transcriptional regulator. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.455 |
cinA | lexA-2 | GLE_3207 | GLE_3205 | Competence/damage-inducible protein CinA; Belongs to the CinA family. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.494 |