GLE_3239 protein (Lysobacter enzymogenes) - STRING interaction network

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[Homology]

Score

GLE_3239

ATPase family associated with various cellular activities (AAA). (1130 aa)

Predicted Functional Partners:

clpP

0.872

clpS

0.823

GLE_1966

0.725

dnaK

0.725

GLE_0084

0.711

grpE

0.694

ruvB

0.662

GLE_2262

0.659

dnaJ

0.632

lon

0.537

Your Current Organism:

Lysobacter enzymogenes

NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLE_0084	GLE_2262	GLE_0084	GLE_2262	Hypothetical protein.	Hsp90xo protein.	0.961
GLE_0084	GLE_3239	GLE_0084	GLE_3239	Hypothetical protein.	ATPase family associated with various cellular activities (AAA).	0.711
GLE_0084	dnaJ	GLE_0084	GLE_2233	Hypothetical protein.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.882
GLE_0084	dnaK	GLE_0084	GLE_2232	Hypothetical protein.	Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.724
GLE_0084	grpE	GLE_0084	GLE_2231	Hypothetical protein.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.962
GLE_0084	lon	GLE_0084	GLE_3416	Hypothetical protein.	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	0.638
GLE_1966	GLE_2262	GLE_1966	GLE_2262	dnaK family protein; Belongs to the heat shock protein 70 family.	Hsp90xo protein.	0.964
GLE_1966	GLE_3239	GLE_1966	GLE_3239	dnaK family protein; Belongs to the heat shock protein 70 family.	ATPase family associated with various cellular activities (AAA).	0.725
GLE_1966	clpP	GLE_1966	GLE_3419	dnaK family protein; Belongs to the heat shock protein 70 family.	ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.446
GLE_1966	dnaJ	GLE_1966	GLE_2233	dnaK family protein; Belongs to the heat shock protein 70 family.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.994
GLE_1966	grpE	GLE_1966	GLE_2231	dnaK family protein; Belongs to the heat shock protein 70 family.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.983
GLE_1966	lon	GLE_1966	GLE_3416	dnaK family protein; Belongs to the heat shock protein 70 family.	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	0.773
GLE_2262	GLE_0084	GLE_2262	GLE_0084	Hsp90xo protein.	Hypothetical protein.	0.961
GLE_2262	GLE_1966	GLE_2262	GLE_1966	Hsp90xo protein.	dnaK family protein; Belongs to the heat shock protein 70 family.	0.964
GLE_2262	GLE_3239	GLE_2262	GLE_3239	Hsp90xo protein.	ATPase family associated with various cellular activities (AAA).	0.659
GLE_2262	clpP	GLE_2262	GLE_3419	Hsp90xo protein.	ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.591
GLE_2262	dnaJ	GLE_2262	GLE_2233	Hsp90xo protein.	Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.990
GLE_2262	dnaK	GLE_2262	GLE_2232	Hsp90xo protein.	Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.964
GLE_2262	grpE	GLE_2262	GLE_2231	Hsp90xo protein.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.886
GLE_2262	lon	GLE_2262	GLE_3416	Hsp90xo protein.	ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.	0.870