| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GLE_2255 | tilS | GLE_2255 | GLE_3394 | UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.810 |
| GLE_4574 | tilS | GLE_4574 | GLE_3394 | Glyoxylase family protein. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.684 |
| gltB | guaA | GLE_0072 | GLE_2893 | Glutamine amidotransferases class-II/glutamate synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.946 |
| gltB | hpt | GLE_0072 | GLE_1719 | Glutamine amidotransferases class-II/glutamate synthase. | Hypoxanthine phosphoribosyltransferase. | 0.630 |
| gltB | tilS | GLE_0072 | GLE_3394 | Glutamine amidotransferases class-II/glutamate synthase. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.893 |
| guaA | gltB | GLE_2893 | GLE_0072 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glutamine amidotransferases class-II/glutamate synthase. | 0.946 |
| guaA | hpt | GLE_2893 | GLE_1719 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine phosphoribosyltransferase. | 0.952 |
| guaA | ndk | GLE_2893 | GLE_2911 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.525 |
| guaA | pth | GLE_2893 | GLE_3807 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.538 |
| guaA | tadA | GLE_2893 | GLE_2885 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.482 |
| guaA | tilS | GLE_2893 | GLE_3394 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.777 |
| hpt | gltB | GLE_1719 | GLE_0072 | Hypoxanthine phosphoribosyltransferase. | Glutamine amidotransferases class-II/glutamate synthase. | 0.630 |
| hpt | guaA | GLE_1719 | GLE_2893 | Hypoxanthine phosphoribosyltransferase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.952 |
| hpt | ndk | GLE_1719 | GLE_2911 | Hypoxanthine phosphoribosyltransferase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.543 |
| hpt | tilS | GLE_1719 | GLE_3394 | Hypoxanthine phosphoribosyltransferase. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.600 |
| ndk | guaA | GLE_2911 | GLE_2893 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.525 |
| ndk | hpt | GLE_2911 | GLE_1719 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Hypoxanthine phosphoribosyltransferase. | 0.543 |
| ndk | tilS | GLE_2911 | GLE_3394 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.733 |
| pth | guaA | GLE_3807 | GLE_2893 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.538 |
| pth | tilS | GLE_3807 | GLE_3394 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.632 |