Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
GLE_3470Membrane protein. (1191 aa)    
Predicted Functional Partners:
GLE_3471
ABC transporter, ATP-binding protein.
 
 
   0.947
GLE_3469
Hypothetical protein.
       0.773
GLE_2532
TonB-dependent receptor.
  
     0.579
GLE_4250
Pyridoxal-phosphate dependent enzyme/CBS domain pair.
     
  0.544
GLE_3468
DEAD/DEAH box helicase/helicase conserved C-terminal domain; Belongs to the DEAD box helicase family.
  
  0.538
GLE_0551
Esterase.
  
     0.483
GLE_4424
Hypothetical protein.
  
     0.446
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.438
GLE_5060
Putative cyanophycinase; Belongs to the peptidase S51 family.
  
     0.431
GLE_0918
Lipoprotein.
  
     0.425
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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