| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GLE_3326 | GLE_3539 | GLE_3326 | GLE_3539 | Acetyltransferase, GNAT family. | Acetyltransferase (GNAT) family. | 0.685 |
| GLE_3539 | GLE_3326 | GLE_3539 | GLE_3326 | Acetyltransferase (GNAT) family. | Acetyltransferase, GNAT family. | 0.685 |
| GLE_3539 | GLE_3540 | GLE_3539 | GLE_3540 | Acetyltransferase (GNAT) family. | UPF0386 protein YjhX. | 0.644 |
| GLE_3539 | acsA | GLE_3539 | GLE_0157 | Acetyltransferase (GNAT) family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.454 |
| GLE_3539 | gcvP | GLE_3539 | GLE_1547 | Acetyltransferase (GNAT) family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.453 |
| GLE_3539 | gltB | GLE_3539 | GLE_0072 | Acetyltransferase (GNAT) family. | Glutamine amidotransferases class-II/glutamate synthase. | 0.616 |
| GLE_3539 | prpE | GLE_3539 | GLE_1286 | Acetyltransferase (GNAT) family. | propionate--CoA ligase. | 0.454 |
| GLE_3540 | GLE_3539 | GLE_3540 | GLE_3539 | UPF0386 protein YjhX. | Acetyltransferase (GNAT) family. | 0.644 |
| acsA | GLE_3539 | GLE_0157 | GLE_3539 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyltransferase (GNAT) family. | 0.454 |
| acsA | gltB | GLE_0157 | GLE_0072 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Glutamine amidotransferases class-II/glutamate synthase. | 0.465 |
| acsA | prpE | GLE_0157 | GLE_1286 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | propionate--CoA ligase. | 0.887 |
| gcvP | GLE_3539 | GLE_1547 | GLE_3539 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Acetyltransferase (GNAT) family. | 0.453 |
| gcvP | gltB | GLE_1547 | GLE_0072 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glutamine amidotransferases class-II/glutamate synthase. | 0.945 |
| gltB | GLE_3539 | GLE_0072 | GLE_3539 | Glutamine amidotransferases class-II/glutamate synthase. | Acetyltransferase (GNAT) family. | 0.616 |
| gltB | acsA | GLE_0072 | GLE_0157 | Glutamine amidotransferases class-II/glutamate synthase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.465 |
| gltB | gcvP | GLE_0072 | GLE_1547 | Glutamine amidotransferases class-II/glutamate synthase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.945 |
| gltB | prpE | GLE_0072 | GLE_1286 | Glutamine amidotransferases class-II/glutamate synthase. | propionate--CoA ligase. | 0.465 |
| prpE | GLE_3539 | GLE_1286 | GLE_3539 | propionate--CoA ligase. | Acetyltransferase (GNAT) family. | 0.454 |
| prpE | acsA | GLE_1286 | GLE_0157 | propionate--CoA ligase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.887 |
| prpE | gltB | GLE_1286 | GLE_0072 | propionate--CoA ligase. | Glutamine amidotransferases class-II/glutamate synthase. | 0.465 |