typA protein (Lysobacter enzymogenes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

typA

GTP-binding protein TypA/BipA. (616 aa)

Predicted Functional Partners:

GLE_3753

0.773

GLE_3755

0.732

GLE_3754

0.727

guaA

0.663

rpsI

0.625

rplA

0.583

gltB

0.578

GLE_3751

0.570

tsf

0.568

rbn-2

0.548

Your Current Organism:

Lysobacter enzymogenes

NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLE_3751	typA	GLE_3751	GLE_3752	Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	GTP-binding protein TypA/BipA.	0.570
GLE_3753	GLE_3754	GLE_3753	GLE_3754	Hypothetical protein.	Hypothetical protein.	0.727
GLE_3753	GLE_3755	GLE_3753	GLE_3755	Hypothetical protein.	Hypothetical protein.	0.727
GLE_3753	typA	GLE_3753	GLE_3752	Hypothetical protein.	GTP-binding protein TypA/BipA.	0.773
GLE_3754	GLE_3753	GLE_3754	GLE_3753	Hypothetical protein.	Hypothetical protein.	0.727
GLE_3754	GLE_3755	GLE_3754	GLE_3755	Hypothetical protein.	Hypothetical protein.	0.773
GLE_3754	typA	GLE_3754	GLE_3752	Hypothetical protein.	GTP-binding protein TypA/BipA.	0.727
GLE_3755	GLE_3753	GLE_3755	GLE_3753	Hypothetical protein.	Hypothetical protein.	0.727
GLE_3755	GLE_3754	GLE_3755	GLE_3754	Hypothetical protein.	Hypothetical protein.	0.773
GLE_3755	typA	GLE_3755	GLE_3752	Hypothetical protein.	GTP-binding protein TypA/BipA.	0.732
gltB	guaA	GLE_0072	GLE_2893	Glutamine amidotransferases class-II/glutamate synthase.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.938
gltB	tsf	GLE_0072	GLE_3363	Glutamine amidotransferases class-II/glutamate synthase.	Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.410
gltB	typA	GLE_0072	GLE_3752	Glutamine amidotransferases class-II/glutamate synthase.	GTP-binding protein TypA/BipA.	0.578
guaA	gltB	GLE_2893	GLE_0072	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Glutamine amidotransferases class-II/glutamate synthase.	0.938
guaA	rplA	GLE_2893	GLE_3800	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.923
guaA	rpsI	GLE_2893	GLE_4259	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.606
guaA	tsf	GLE_2893	GLE_3363	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.618
guaA	typA	GLE_2893	GLE_3752	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GTP-binding protein TypA/BipA.	0.663
rbn-2	typA	GLE_3830	GLE_3752	tRNA-processing ribonuclease BN.	GTP-binding protein TypA/BipA.	0.548
rplA	guaA	GLE_3800	GLE_2893	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.923