| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GLE_0829 | bioA | GLE_0829 | GLE_3946 | Aspartate kinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.696 |
| GLE_0829 | gltB | GLE_0829 | GLE_0072 | Aspartate kinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Glutamine amidotransferases class-II/glutamate synthase. | 0.802 |
| GLE_0829 | lysA | GLE_0829 | GLE_3732 | Aspartate kinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.987 |
| GLE_2101 | GLE_4894 | GLE_2101 | GLE_4894 | Aminotransferase, classes I, II, and III/beta-eliminating lyase. | Amino acid adenylation domain protein. | 0.684 |
| GLE_2101 | bioA | GLE_2101 | GLE_3946 | Aminotransferase, classes I, II, and III/beta-eliminating lyase. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.730 |
| GLE_2101 | bioB | GLE_2101 | GLE_0061 | Aminotransferase, classes I, II, and III/beta-eliminating lyase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.783 |
| GLE_2101 | bioD | GLE_2101 | GLE_0718 | Aminotransferase, classes I, II, and III/beta-eliminating lyase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.882 |
| GLE_2101 | bioF | GLE_2101 | GLE_0062 | Aminotransferase, classes I, II, and III/beta-eliminating lyase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.492 |
| GLE_3947 | bioA | GLE_3947 | GLE_3946 | Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.864 |
| GLE_3947 | nudE | GLE_3947 | GLE_3945 | Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | ADP compounds hydrolase. | 0.738 |
| GLE_4894 | GLE_2101 | GLE_4894 | GLE_2101 | Amino acid adenylation domain protein. | Aminotransferase, classes I, II, and III/beta-eliminating lyase. | 0.684 |
| GLE_4894 | bioA | GLE_4894 | GLE_3946 | Amino acid adenylation domain protein. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.693 |
| GLE_4894 | bioF | GLE_4894 | GLE_0062 | Amino acid adenylation domain protein. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.684 |
| GLE_4894 | gltB | GLE_4894 | GLE_0072 | Amino acid adenylation domain protein. | Glutamine amidotransferases class-II/glutamate synthase. | 0.695 |
| GLE_4894 | lysA | GLE_4894 | GLE_3732 | Amino acid adenylation domain protein. | Aspartate kinase/diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.639 |
| bioA | GLE_0829 | GLE_3946 | GLE_0829 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aspartate kinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.696 |
| bioA | GLE_2101 | GLE_3946 | GLE_2101 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aminotransferase, classes I, II, and III/beta-eliminating lyase. | 0.730 |
| bioA | GLE_3947 | GLE_3946 | GLE_3947 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.864 |
| bioA | GLE_4894 | GLE_3946 | GLE_4894 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Amino acid adenylation domain protein. | 0.693 |
| bioA | bioB | GLE_3946 | GLE_0061 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.992 |