Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilCType IV pilus assembly protein. (418 aa)    
Predicted Functional Partners:
pilB
Type IV pilus assembly protein.
 
 0.997
pilD
Type IV prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.982
gspE
General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 0.978
pilQ
Type IV assembly protein.
 
 
 
 0.922
pilM
Type IV pilus assembly protein.
 
 
 
 0.919
pilU
Type IV pilus assembly protein.
  
   
 0.890
pilT
Type IV pilus assembly protein.
 
   
 0.882
pilU-2
Type IV pilus assembly protein.
  
   
 0.876
pilO
Type IV assembly protein.
 
 
 
 0.848
pilN
Type IV pilus assembly protein.
 
 
 
 0.837
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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