| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GLE_4157 | GLE_4158 | GLE_4157 | GLE_4158 | Hypothetical protein. | Hypothetical protein. | 0.723 |
| GLE_4157 | GLE_4160 | GLE_4157 | GLE_4160 | Hypothetical protein. | TonB family C-terminal domain. | 0.413 |
| GLE_4157 | nrdR | GLE_4157 | GLE_4159 | Hypothetical protein. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.507 |
| GLE_4157 | ribD | GLE_4157 | GLE_4156 | Hypothetical protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.773 |
| GLE_4158 | GLE_4157 | GLE_4158 | GLE_4157 | Hypothetical protein. | Hypothetical protein. | 0.723 |
| GLE_4158 | GLE_4160 | GLE_4158 | GLE_4160 | Hypothetical protein. | TonB family C-terminal domain. | 0.437 |
| GLE_4158 | nrdR | GLE_4158 | GLE_4159 | Hypothetical protein. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.539 |
| GLE_4158 | ribD | GLE_4158 | GLE_4156 | Hypothetical protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.723 |
| GLE_4160 | GLE_4157 | GLE_4160 | GLE_4157 | TonB family C-terminal domain. | Hypothetical protein. | 0.413 |
| GLE_4160 | GLE_4158 | GLE_4160 | GLE_4158 | TonB family C-terminal domain. | Hypothetical protein. | 0.437 |
| GLE_4160 | glyA | GLE_4160 | GLE_4161 | TonB family C-terminal domain. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.480 |
| GLE_4160 | nrdR | GLE_4160 | GLE_4159 | TonB family C-terminal domain. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.613 |
| GLE_4160 | ribD | GLE_4160 | GLE_4156 | TonB family C-terminal domain. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.413 |
| glyA | GLE_4160 | GLE_4161 | GLE_4160 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TonB family C-terminal domain. | 0.480 |
| glyA | nrdR | GLE_4161 | GLE_4159 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.702 |
| glyA | ribD | GLE_4161 | GLE_4156 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.607 |
| nrdR | GLE_4157 | GLE_4159 | GLE_4157 | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Hypothetical protein. | 0.507 |
| nrdR | GLE_4158 | GLE_4159 | GLE_4158 | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Hypothetical protein. | 0.539 |
| nrdR | GLE_4160 | GLE_4159 | GLE_4160 | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | TonB family C-terminal domain. | 0.613 |
| nrdR | glyA | GLE_4159 | GLE_4161 | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.702 |