Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (324 aa)    
Predicted Functional Partners:
GLE_4243
NAD dependent epimerase/dehydratase family protein.
 
0.985
manA
Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.969
GLE_2246
Glycosyl transferase, group 1 family protein.
  
 
 0.903
GLE_4246
ABC-2 type transporter.
 
  
 0.888
GLE_4245
ABC transporter, ATP-binding protein.
   
 0.887
GLE_4247
Glycosyl transferase, group 1 family protein.
 
 
 0.876
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
   0.873
GLE_2455
Undecaprenyl-phosphate glucose phosphotransferase.
 
  
 0.862
GLE_2920
Epimerase/dehydratase.
  
  
 0.861
GLE_4244
Methyltransferase type 11.
 
   
 0.855
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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