Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
GLE_4282DNA-binding response regulator. (224 aa)    
Predicted Functional Partners:
GLE_4281
Sensor histidine kinase.
 
  0.921
GLE_1781
Putative heavy metal histidine sensor kinase; Member of a two-component regulatory system.
 
  0.896
GLE_0632
Sensory box histidine kinase.
  
 0.891
GLE_4322
Sensor histidine kinase.
  
  0.844
GLE_4341
Sensor histidine kinase.
 
 0.844
GLE_2565
Histidine kinase.
  
  0.808
GLE_5248
Sensor histidine kinase.
  
 0.792
GLE_4753
Sensor histidine kinase.
  
 
  0.779
GLE_0593
Histidine kinase family protein.
  
 0.773
GLE_4903
Sensor histidine kinase.
  
 0.729
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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