GLE_4371 protein (Lysobacter enzymogenes) - STRING interaction network

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GLE_4371

N-acetylmuramoyl-L-alanine amidase. (274 aa)

Predicted Functional Partners:

anmK

0.553

nagZ

0.548

GLE_0260

0.538

ftsI

0.527

mrdA

0.503

mrcA

0.480

GLE_2406

0.471

mpl

0.445

GLE_3671

0.436

GLE_2506

0.432

Your Current Organism:

Lysobacter enzymogenes

NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLE_0260	GLE_4371	GLE_0260	GLE_4371	Major facilitator superfamily MFS_1, putative.	N-acetylmuramoyl-L-alanine amidase.	0.538
GLE_0260	anmK	GLE_0260	GLE_0262	Major facilitator superfamily MFS_1, putative.	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	0.598
GLE_0260	nagZ	GLE_0260	GLE_1718	Major facilitator superfamily MFS_1, putative.	Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.	0.660
GLE_2406	GLE_4371	GLE_2406	GLE_4371	Oxidoreductase.	N-acetylmuramoyl-L-alanine amidase.	0.471
GLE_2506	GLE_4371	GLE_2506	GLE_4371	Hypothetical protein.	N-acetylmuramoyl-L-alanine amidase.	0.432
GLE_3671	GLE_4371	GLE_3671	GLE_4371	Hypothetical protein.	N-acetylmuramoyl-L-alanine amidase.	0.436
GLE_4371	GLE_0260	GLE_4371	GLE_0260	N-acetylmuramoyl-L-alanine amidase.	Major facilitator superfamily MFS_1, putative.	0.538
GLE_4371	GLE_2406	GLE_4371	GLE_2406	N-acetylmuramoyl-L-alanine amidase.	Oxidoreductase.	0.471
GLE_4371	GLE_2506	GLE_4371	GLE_2506	N-acetylmuramoyl-L-alanine amidase.	Hypothetical protein.	0.432
GLE_4371	GLE_3671	GLE_4371	GLE_3671	N-acetylmuramoyl-L-alanine amidase.	Hypothetical protein.	0.436
GLE_4371	anmK	GLE_4371	GLE_0262	N-acetylmuramoyl-L-alanine amidase.	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	0.553
GLE_4371	ftsI	GLE_4371	GLE_4136	N-acetylmuramoyl-L-alanine amidase.	Penicillin binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.527
GLE_4371	mpl	GLE_4371	GLE_0859	N-acetylmuramoyl-L-alanine amidase.	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.	0.445
GLE_4371	mrcA	GLE_4371	GLE_0931	N-acetylmuramoyl-L-alanine amidase.	Penicillin-binding protein 1A.	0.480
GLE_4371	mrdA	GLE_4371	GLE_4510	N-acetylmuramoyl-L-alanine amidase.	Penicillin binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.503
GLE_4371	nagZ	GLE_4371	GLE_1718	N-acetylmuramoyl-L-alanine amidase.	Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.	0.548
anmK	GLE_0260	GLE_0262	GLE_0260	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	Major facilitator superfamily MFS_1, putative.	0.598
anmK	GLE_4371	GLE_0262	GLE_4371	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	N-acetylmuramoyl-L-alanine amidase.	0.553
anmK	mpl	GLE_0262	GLE_0859	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.	0.442
anmK	nagZ	GLE_0262	GLE_1718	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.	0.763