Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GLE_4788Aminotransferase class I and II/beta-eliminating lyase. (416 aa)    
Predicted Functional Partners:
gltB
Glutamine amidotransferases class-II/glutamate synthase.
    
 0.947
maeB
NADP-dependent malic enzyme.
 
 0.926
GLE_2691
Bacterial NAD-glutamate dehydrogenase family protein.
  
  
 0.898
ilvD
Dehydratase family; Belongs to the IlvD/Edd family.
   
 
 0.883
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
     
 0.881
GLE_1976
Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.879
ald
Alanine dehydrogenase.
     
 0.878
ilvE
Branched-chain amino acid aminotransferase.
    
 0.877
ilvE-2
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.877
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.873
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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