Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GLE_5043acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)    
Predicted Functional Partners:
fadJ
Fatty acid oxidation complex subunit alpha.
 0.999
fadB
3-hydroxyacyl-CoA dehydrogenase.
 
 0.999
GLE_1096
acyl-CoA dehydrogenase, C-terminal domain.
 
 0.968
GLE_2346
acyl-CoA dehydrogenase.
  
 0.929
mvaB
Hydroxymethylglutaryl-CoA lyase.
  
 
 0.910
GLE_4228
3-oxoacid CoA-transferase, A subunit family.
  
 
 0.908
scoB
succinyl-CoA:3-ketoacid-coenzyme A transferase, subunit B.
  
 
 0.906
GLE_1971
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.905
GLE_2914
3-ketoacyl-CoA thiolase A; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.903
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.899
Your Current Organism:
Lysobacter enzymogenes
NCBI taxonomy Id: 69
Other names: ATCC 29487, DSM 2043, L. enzymogenes, LMG 8762, LMG:8762, Lysobacter enzymogenes subsp. enzymogenes, UASM 495
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